Preexisting heart failure with reduced ejection fraction attenuates renal fibrosis after ischemia reperfusion via sympathetic activation

Although chronic heart failure is clinically associated with acute kidney injury (AKI), the precise mechanism that connects kidney and heart remains unknown. Here, we elucidate the effect of pre-existing heart failure with reduced ejection fraction (HFrEF) on kidney via sympathetic activity, using t...

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Publicat a:Sci Rep
Autors principals: Matsuura, Ryo, Yamashita, Tetsushi, Hayase, Naoki, Hamasaki, Yoshifumi, Noiri, Eisei, Numata, Genri, Takimoto, Eiki, Nangaku, Masaomi, Doi, Kent
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302613/
https://ncbi.nlm.nih.gov/pubmed/34302012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94617-3
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