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Atomistic Basis of Microtubule Dynamic Instability Assessed Via Multiscale Modeling
Microtubule “dynamic instability,” the abrupt switching from assembly to disassembly caused by the hydrolysis of GTP to GDP within the β subunit of the αβ-tubulin heterodimer, is necessary for vital cellular processes such as mitosis and migration. Despite existing high-resolution structural data, t...
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| Publicado no: | Ann Biomed Eng |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8302526/ https://ncbi.nlm.nih.gov/pubmed/33537926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-020-02715-6 |
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