Population pharmacokinetic modeling of molibresib and its active metabolites in patients with solid tumors: A semimechanistic autoinduction model

Molibresib (GSK525762) is an investigational, orally bioavailable, small‐molecule bromodomain and extraterminal (BET) protein inhibitor for the treatment of advanced solid tumors. Molibresib was initially evaluated in a first‐time‐in‐human (FTIH) study BET115521 consisting of two parts: Part 1 of th...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:CPT Pharmacometrics Syst Pharmacol
Main Authors: Krishnatry, Anu Shilpa, Voelkner, Alexander, Dhar, Arindam, Prohn, Marita, Ferron‐Brady, Geraldine
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302244/
https://ncbi.nlm.nih.gov/pubmed/33955700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12639
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares