Memantine and Riluzole Exacerbate, Rather Than Ameliorate Behavioral Deficits Induced by 8-OH-DPAT Sensitization in a Spatial Task

Chronic sensitization to serotonin 1A and 7 receptors agonist 8-OH-DPAT induces compulsive checking and perseverative behavior. As such, it has been used to model obsessive-compulsive disorder (OCD)-like behavior in mice and rats. In this study, we tested spatial learning in the 8-OH-DPAT model of O...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Janikova, Martina, Mainerova, Karolina, Vojtechova, Iveta, Petrasek, Tomas, Svoboda, Jan, Stuchlik, Ales
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301967/
https://ncbi.nlm.nih.gov/pubmed/34356631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071007
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