DDR1 Affects Metabolic Reprogramming in Breast Cancer Cells by Cross-Talking to the Insulin/IGF System

The insulin receptor isoform A (IR-A), a dual receptor for insulin and IGF2, plays a role in breast cancer (BC) progression and metabolic reprogramming. Notably, discoidin domain receptor 1 (DDR1), a collagen receptor often dysregulated in cancer, is involved in a functional crosstalk and feed forwa...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Vella, Veronica, Giuliano, Marika, Nicolosi, Maria Luisa, Majorana, Maria Giovanna, Marć, Małgorzata Anna, Muoio, Maria Grazia, Morrione, Andrea, Maggiolini, Marcello, Lappano, Rosamaria, De Francesco, Ernestina Marianna, Belfiore, Antonino
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301864/
https://ncbi.nlm.nih.gov/pubmed/34206590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11070926
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