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Enzymatic and Chemical Syntheses of Vacor Analogs of Nicotinamide Riboside, NMN and NAD

It has recently been demonstrated that the rat poison vacor interferes with mammalian NAD metabolism, because it acts as a nicotinamide analog and is converted by enzymes of the NAD salvage pathway. Thereby, vacor is transformed into the NAD analog vacor adenine dinucleotide (VAD), a molecule that c...

詳細記述

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書誌詳細
出版年:Biomolecules
主要な著者: Sverkeli, Lars Jansen, Hayat, Faisal, Migaud, Marie E., Ziegler, Mathias
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301822/
https://ncbi.nlm.nih.gov/pubmed/34356669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071044
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