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Nicotinamide riboside–amino acid conjugates that are stable to purine nucleoside phosphorylase

The nutraceutical Nicotinamide Riboside (NR), an efficacious biosynthetic precursor to NAD, is readily metabolized by the purine nucleoside phosphorylase (PNP). Access to the PNP-stable versions of NR is difficult because the glycosidic bond of NR is easily cleaved. Unlike NR, NRH, the reduced form...

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Bibliografische gegevens
Gepubliceerd in:Org Biomol Chem
Hoofdauteurs: Hayat, Faisal, Migaud, Marie E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953427/
https://ncbi.nlm.nih.gov/pubmed/32236231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob00134a
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