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Nicotinamide riboside–amino acid conjugates that are stable to purine nucleoside phosphorylase
The nutraceutical Nicotinamide Riboside (NR), an efficacious biosynthetic precursor to NAD, is readily metabolized by the purine nucleoside phosphorylase (PNP). Access to the PNP-stable versions of NR is difficult because the glycosidic bond of NR is easily cleaved. Unlike NR, NRH, the reduced form...
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| izdano v: | Org Biomol Chem |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7953427/ https://ncbi.nlm.nih.gov/pubmed/32236231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob00134a |
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