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Comprehensive in vitro pro‐arrhythmic assays demonstrate that omecamtiv mecarbil has low pro‐arrhythmic risk

Omecamtiv mecarbil (OM) is a myosin activator (myotrope), developed as a potential therapeutic agent for heart failure with reduced ejection fraction. To characterize the potential pro‐arrhythmic risk of this novel sarcomere activator, we evaluated OM in a series of International Conference on Harmo...

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Vydáno v:Clin Transl Sci
Hlavní autoři: Qu, Yusheng, Gao, BaoXi, Arimura, Ziva, Fang, Mei, Vargas, Hugo M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301593/
https://ncbi.nlm.nih.gov/pubmed/33955165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.13039
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