Glucose-Dependent Insulinotropic Polypeptide Suppresses Foam Cell Formation of Macrophages through Inhibition of the Cyclin-Dependent Kinase 5-CD36 Pathway

Glucose-dependent insulinotropic polypeptide (GIP) has been reported to have an atheroprotective property in animal models. However, the effect of GIP on macrophage foam cell formation, a crucial step of atherosclerosis, remains largely unknown. We investigated the effects of GIP on foam cell format...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Terasaki, Michishige, Yashima, Hironori, Mori, Yusaku, Saito, Tomomi, Shiraga, Yoshie, Kawakami, Raichi, Ohara, Makoto, Fukui, Tomoyasu, Hirano, Tsutomu, Yamada, Yuichiro, Seino, Yutaka, Yamagishi, Sho-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301338/
https://ncbi.nlm.nih.gov/pubmed/34356896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9070832
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