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An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation in Nuclear Respiratory Factor 1 (Nrf1) Altering the DNA Methylation State and Correct Embryonic Development

SIMPLE SUMMARY: In this work, we aimed to discover unknown genes that are important in the regulation of other genes. These genes often play an important role during the development of the embryo. By screening thousands of mice, we found a gene, namely, Nuclear Respiratory Factor 1 (Nrf1), that cont...

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Publicado en:Animals (Basel)
Main Authors: Sorolla, Maria Alba, Marqués, Marta, Parisi, Eva, Sorolla, Anabel
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300126/
https://ncbi.nlm.nih.gov/pubmed/34359231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani11072103
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