Placental mitochondrial DNA mutational load and perinatal outcomes: findings from a multi-ethnic pregnancy cohort

Mitochondria fuel placental activity, with mitochondrial dysfunction implicated in several perinatal complications. We investigated placental mtDNA mutational load using NextGen sequencing in relation to birthweight and gestational length among 358 mother-newborn pairs. We found that higher heteropl...

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Bibliografski detalji
Izdano u:Mitochondrion
Glavni autori: Cowell, Whitney, Brunst, Kelly, Colicino, Elena, Zhang, Li, Zhang, Xiang, Bloomquist, Tessa R., Baccarelli, Andrea A., Wright, Rosalind J.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299859/
https://ncbi.nlm.nih.gov/pubmed/34102325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2021.06.006
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