Placental mitochondrial DNA mutational load and perinatal outcomes: findings from a multi-ethnic pregnancy cohort

Mitochondria fuel placental activity, with mitochondrial dysfunction implicated in several perinatal complications. We investigated placental mtDNA mutational load using NextGen sequencing in relation to birthweight and gestational length among 358 mother-newborn pairs. We found that higher heteropl...

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Detalhes bibliográficos
Publicado no:Mitochondrion
Main Authors: Cowell, Whitney, Brunst, Kelly, Colicino, Elena, Zhang, Li, Zhang, Xiang, Bloomquist, Tessa R., Baccarelli, Andrea A., Wright, Rosalind J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299859/
https://ncbi.nlm.nih.gov/pubmed/34102325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2021.06.006
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