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Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity

Group 2 innate lymphoid cells (ILC2s) are tissue resident in the lung and activated by inhaled allergens via epithelial-derived alarmins including IL-33. Activated ILC2s proliferate, produce IL-5 and IL-13, and induce eosinophilic inflammation. Here, we report that intranasal IL-33 or the protease a...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Mathä, Laura, Romera-Hernández, Mónica, Steer, Catherine A., Yin, Yi Han, Orangi, Mona, Shim, Hanjoo, Chang, ChihKai, Rossi, Fabio M., Takei, Fumio
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299566/
https://ncbi.nlm.nih.gov/pubmed/34305911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.679509
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