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Lung group 2 innate lymphoid cells are trained by endogenous IL-33 in the neonatal period
Group 2 innate lymphoid cells (ILC2s) in mouse lungs are activated by the epithelium-derived alarmin IL-33. Activated ILC2s proliferate and produce IL-5 and IL-13 that drive allergic responses. In neonatal lungs, the occurrence of spontaneous activation of lung ILC2s is dependent on endogenous IL-33...
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| Publié dans: | JCI Insight |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7453888/ https://ncbi.nlm.nih.gov/pubmed/32573494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135961 |
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