BDNF and COMT, but not APOE, Alleles are Associated with Psychiatric Symptoms in Refractory Epilepsy

OBJECTIVE: To determine whether three common genetic polymorphisms [apolipoprotein (APOE) ε4 (rs42938 and rs7412), brain derived neurotrophic factor (BDNF) Met (rs6265), and Catechol-O-Methyltransferase (COMT) Val (rs4680)] are associated with increased psychiatric symptomatology in individuals with...

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Publicat a:Epilepsy Behav
Autors principals: Doherty, Christine, Hogue, Olivia, Floden, Darlene P., Altemus, Jessica B., Najm, Imad M., Eng, Charis, Busch, Robyn M.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299517/
https://ncbi.nlm.nih.gov/pubmed/30909076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2019.02.032
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