CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that affects 1% of the population. CS-semi5 is a semisynthetic chondroitin sulfate. In this study, CS-semi5 was shown to have positive effects on a model of collagen-induced arthritis (CIA). CS-semi5 treatment had obvious effects on...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Li, Xiang, Tang, Xiaonan, Wang, Yufei, Chai, Changwei, Zhao, Zhehui, Zhang, Haijing, Peng, Ying, Wu, Lianqiu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298759/
https://ncbi.nlm.nih.gov/pubmed/34305585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.655101
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