Colitis Is Effectively Ameliorated by (±)-8-Acetonyl-dihydrocoptisine via the XBP1-NF-κB Pathway

Ulcerative colitis (UC) is a recurrent, chronic intestinal disease. Available treatments for UC are poor effective and/or cause severe adverse events. X-box binding protein 1 (XBP1) and nuclear factor-κB (NF-κB) have been reported to play important roles in UC. Specifically, deletion or downregulati...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Zhang, HaiJing, Song, GuangMing, Zhang, ZhiHui, Song, HuaChen, Tang, XiaoNan, Deng, AnJun, Wang, WenJie, Wu, LianQiu, Qin, HaiLin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591823/
https://ncbi.nlm.nih.gov/pubmed/28928666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00619
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