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CYP2D6 phenotype explains reported yohimbine concentrations in four severe acute intoxications

The indole alkaloid yohimbine is an alpha-2 receptor antagonist used for its sympathomimetic effects. Several cases of yohimbine intoxication have been reported and the most recent one involved four individuals taking a yohimbine-containing drug powder. All individuals developed severe intoxication...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Mueller-Schoell, Anna, Michelet, Robin, Weinelt, Ferdinand, Kloft, Charlotte, Mikus, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298364/
https://ncbi.nlm.nih.gov/pubmed/34027562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-03082-4
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