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Validation of the in vitro comet assay for DNA cross-links and altered bases detection
Mechanistic toxicology is gaining weight for human health risk assessment. Different mechanistic assays are available, such as the comet assay, which detects DNA damage at the level of individual cells. However, the conventional alkaline version only detects strand breaks and alkali-labile sites. We...
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| Publicado no: | Arch Toxicol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8298235/ https://ncbi.nlm.nih.gov/pubmed/34196753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-03102-3 |
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