C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia

Transcription factor MYB has recently emerged as a promising drug target for the treatment of acute myeloid leukemia (AML). Here, we have characterized a group of natural sesquiterpene lactones (STLs), previously shown to suppress MYB activity, for their potential to decrease AML cell proliferation....

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Publicat a:Oncogene
Autors principals: Yusenko, Maria V., Trentmann, Amke, Casolari, Debora A., Abdel Ghani, Luca, Lenz, Mairin, Horn, Melanie, Dörner, Wolfgang, Klempnauer, Stefan, Mootz, Henning D., Arteaga, Maria Francisca, Mikesch, Jan-Henrik, D’Andrea, Richard J., Gonda, Thomas J., Müller-Tidow, Carsten, Schmidt, Thomas J., Klempnauer, Karl-Heinz
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298201/
https://ncbi.nlm.nih.gov/pubmed/33958723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01800-x
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