Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis

BACKGROUND: The pathogenesis of contact dermatitis, a common inflammatory skin disease with limited treatment options, is held to be driven by inflammasome activation induced by allergens and irritants. We here aim to identify inflammasome‐targeting treatment strategies for irritant contact dermatit...

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Detalhes bibliográficos
Publicado no:Clin Transl Allergy
Main Authors: Bonnekoh, Hanna, Vera, Carolina, Abad‐Perez, Angela, Radetzki, Silke, Neuenschwander, Martin, Specker, Edgar, Mahnke, Niklas Amadeus, Frischbutter, Stefan, Latz, Eicke, Nazaré, Marc, Kries, Jens v., Maurer, Marcus, Scheffel, Jörg, Krause, Karoline
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297992/
https://ncbi.nlm.nih.gov/pubmed/34322217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clt2.12045
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