SOCS3 deficiency in cardiomyocytes elevates sensitivity of ischemic preconditioning that synergistically ameliorates myocardial ischemia reperfusion injury

Ischemic preconditioning (IPC) is the most powerful endogenous cardioprotective form of cellular adaptation. However, the inhibitory or augmenting mechanism underlying cardioprotection via IPC remains largely unknown. Suppressor of cytokine signaling-3 (SOCS3) is a cytokine-inducible potent negative...

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Publicado en:PLoS One
Autores principales: Nohara, Shoichiro, Yamamoto, Mai, Yasukawa, Hideo, Nagata, Takanobu, Takahashi, Jinya, Shimozono, Koutatsu, Yanai, Toshiyuki, Sasaki, Tomoko, Okabe, Kota, Shibata, Tatsuhiro, Akagaki, Daiki, Mawatari, Kazutoshi, Fukumoto, Yoshihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297769/
https://ncbi.nlm.nih.gov/pubmed/34292971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254712
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