SOCS3 deficiency in cardiomyocytes elevates sensitivity of ischemic preconditioning that synergistically ameliorates myocardial ischemia reperfusion injury

Ischemic preconditioning (IPC) is the most powerful endogenous cardioprotective form of cellular adaptation. However, the inhibitory or augmenting mechanism underlying cardioprotection via IPC remains largely unknown. Suppressor of cytokine signaling-3 (SOCS3) is a cytokine-inducible potent negative...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nohara, Shoichiro, Yamamoto, Mai, Yasukawa, Hideo, Nagata, Takanobu, Takahashi, Jinya, Shimozono, Koutatsu, Yanai, Toshiyuki, Sasaki, Tomoko, Okabe, Kota, Shibata, Tatsuhiro, Akagaki, Daiki, Mawatari, Kazutoshi, Fukumoto, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297769/
https://ncbi.nlm.nih.gov/pubmed/34292971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254712
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