Dexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice

BACKGROUND: Several studies stablished a relationship between metabolic disturbances and Alzheimer´s disease (AD) where inflammation plays a pivotal role. However, mechanisms involved still remain unclear. In the present study, we aimed to evaluate central and peripheral effects of dexibuprofen (DXI...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Ettcheto, Miren, Sánchez-Lopez, Elena, Cano, Amanda, Carrasco, Marina, Herrera, Katherine, Manzine, Patricia R., Espinosa-Jimenez, Triana, Busquets, Oriol, Verdaguer, Ester, Olloquequi, Jordi, Auladell, Carme, Folch, Jaume, Camins, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296685/
https://ncbi.nlm.nih.gov/pubmed/34294142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00646-w
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