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Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways

The aim of the present study is to elucidate the neuronal pathways associated to NSAIDs causing a reduction of the risk and progression of Alzheimer's disease. The research was developed administering the active enantiomer of ibuprofen, dexibuprofen (DXI), in order to reduce associated gastric...

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Detalles Bibliográficos
Publicado en:Redox Biol
Autores principales: Ettcheto, Miren, Sánchez-López, Elena, Pons, Laura, Busquets, Oriol, Olloquequi, Jordi, Beas-Zarate, Carlos, Pallas, Merce, García, Maria Luisa, Auladell, Carme, Folch, Jaume, Camins, Antoni
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480981/
https://ncbi.nlm.nih.gov/pubmed/28646794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.06.003
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