Causes of altered ventricular mechanics in hypertrophic cardiomyopathy: an in-silico study

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is typically caused by mutations in sarcomeric genes leading to cardiomyocyte disarray, replacement fibrosis, impaired contractility, and elevated filling pressures. These varying tissue properties are associated with certain strain patterns that may all...

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Dades bibliogràfiques
Publicat a:Biomed Eng Online
Autors principals: Kovacheva, Ekaterina, Gerach, Tobias, Schuler, Steffen, Ochs, Marco, Dössel, Olaf, Loewe, Axel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296558/
https://ncbi.nlm.nih.gov/pubmed/34294108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12938-021-00900-9
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