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Causes of altered ventricular mechanics in hypertrophic cardiomyopathy: an in-silico study

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is typically caused by mutations in sarcomeric genes leading to cardiomyocyte disarray, replacement fibrosis, impaired contractility, and elevated filling pressures. These varying tissue properties are associated with certain strain patterns that may all...

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Detalhes bibliográficos
Publicado no:Biomed Eng Online
Main Authors: Kovacheva, Ekaterina, Gerach, Tobias, Schuler, Steffen, Ochs, Marco, Dössel, Olaf, Loewe, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296558/
https://ncbi.nlm.nih.gov/pubmed/34294108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12938-021-00900-9
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