Competitive blocking of salivary gland [(18)F]DCFPyL uptake via localized, retrograde ductal injection of non-radioactive DCFPyL: a preclinical study

BACKGROUND: PSMA-targeted radionuclide therapy (TRT) is a promising treatment for prostate cancer (PCa), but dose-limiting xerostomia can severely limit its clinical adaptation, especially when using alpha-emitting radionuclides. With [(18)F]DCFPyL as a surrogate for PSMA-TRT, we report a novel meth...

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書誌詳細
出版年:EJNMMI Res
主要な著者: Roy, Jyoti, Warner, Blake M., Basuli, Falguni, Zhang, Xiang, Zheng, Changyu, Goldsmith, Corrine, Phelps, Tim, Wong, Karen, Ton, Anita T., Pieschl, Rick, White, Margaret E., Swenson, Rolf, Chiorini, John A., Choyke, Peter L., Lin, Frank I.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2021
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295433/
https://ncbi.nlm.nih.gov/pubmed/34287731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-021-00803-9
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