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The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores

All membrane fusion reactions proceed through an initial fusion pore, including calcium-triggered release of neurotransmitters and hormones. Expansion of this small pore to release cargo is energetically costly and regulated by cells, but the mechanisms are poorly understood. Here, we show that the...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Wu, Zhenyong, Dharan, Nadiv, McDargh, Zachary A, Thiyagarajan, Sathish, O'Shaughnessy, Ben, Karatekin, Erdem
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294851/
https://ncbi.nlm.nih.gov/pubmed/34190041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.68215
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