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The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores

All membrane fusion reactions proceed through an initial fusion pore, including calcium-triggered release of neurotransmitters and hormones. Expansion of this small pore to release cargo is energetically costly and regulated by cells, but the mechanisms are poorly understood. Here, we show that the...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Wu, Zhenyong, Dharan, Nadiv, McDargh, Zachary A, Thiyagarajan, Sathish, O'Shaughnessy, Ben, Karatekin, Erdem
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294851/
https://ncbi.nlm.nih.gov/pubmed/34190041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.68215
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