Imlifidase Desensitization in Crossmatch-positive, Highly Sensitized Kidney Transplant Recipients: Results of an International Phase 2 Trial (Highdes)

Highly HLA sensitized patients have limited access to life-saving kidney transplantation because of a paucity of immunologically suitable donors. Imlifidase is a cysteine protease that cleaves IgG leading to a rapid decrease in antibody level and inhibition of IgG-mediated injury. This study investi...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Jordan, Stanley C., Legendre, Christophe, Desai, Niraj M., Lorant, Tomas, Bengtsson, Mats, Lonze, Bonnie E., Vo, Ashley A., Runström, Anna, Laxmyr, Lena, Sjöholm, Kristoffer, Schiött, Åsa, Sonesson, Elisabeth, Wood, Kathryn, Winstedt, Lena, Kjellman, Christian, Montgomery, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Original Clinical Science—General
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294837/
https://ncbi.nlm.nih.gov/pubmed/33093408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000003496
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