Загрузка...
LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology
Swelling-activated volume-regulated anion channels (VRACs) are heteromeric channels comprising LRRC8A and at least one other LRRC8 paralog. Cryoelectron microscopy (cryo-EM) structures of nonnative LRRC8A and LRRC8D homohexamers have been described. We demonstrate here that LRRC8A homohexamers poorl...
Сохранить в:
| Опубликовано в: : | Am J Physiol Cell Physiol |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2021
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8294627/ https://ncbi.nlm.nih.gov/pubmed/33356947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00454.2020 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|