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Intracellular and extracellular loops of LRRC8 are essential for volume-regulated anion channel function
The volume-regulated anion channel (VRAC) is expressed ubiquitously in vertebrate cells and mediates swelling-induced release of Cl(−) and organic solutes. Recent studies by several laboratories have demonstrated conclusively that VRAC is encoded by members of the leucine-rich repeat containing 8 (L...
Gespeichert in:
| Veröffentlicht in: | J Gen Physiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028502/ https://ncbi.nlm.nih.gov/pubmed/29853476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812016 |
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