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Thermoplastic Nanofluidic Devices for Identifying Abasic Sites in Single DNA Molecules
DNA damage can take many forms such as double-strand breaks and/or the formation of abasic (apurinic/apyrimidinic; AP) sites. The presence of AP sites can be used to determine therapeutic efficacy of many drugs, such as doxorubicin. While there are different assays to search for DNA damage, they are...
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| Publicado en: | Lab Chip |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8293902/ https://ncbi.nlm.nih.gov/pubmed/33651049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0lc01038c |
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