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Identification of a triple drug combination that is synergistically cytotoxic for triple-negative breast cancer cells using a novel combination discovery approach

Triple-negative breast cancer (TNBC) is a very aggressive form of breast cancer with few molecularly targeted therapies. We used a novel unbiased approach to identify higher order synergistic or enhancer combinations of marketed kinase inhibitor drugs that inhibit cell viability of TNBC cell lines....

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Ahmad, Syed, He, Qingping, Williams, Kevin P., Scott, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293681/
https://ncbi.nlm.nih.gov/pubmed/32441190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220924478
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