Triple Combination of Ascorbate, Menadione and the Inhibition of Peroxiredoxin-1 Produces Synergistic Cytotoxic Effects in Triple-Negative Breast Cancer Cells

Triple-negative breast cancer (TNBC) is an aggressive form of mammary malignancy currently without satisfactory systemic treatment options. Agents generating reactive oxygen species (ROS), such as ascorbate (Asc) and menadione (Men), especially applied in combination, have been proposed as an altern...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Bajor, Malgorzata, Graczyk-Jarzynka, Agnieszka, Marhelava, Katsiaryna, Kurkowiak, Malgorzata, Rahman, Arman, Aura, Claudia, Russell, Niamh, Zych, Agata O., Firczuk, Malgorzata, Winiarska, Magdalena, Gallagher, William M., Zagozdzon, Radoslaw
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222372/
https://ncbi.nlm.nih.gov/pubmed/32316111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9040320
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