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Targeting Negative and Positive Immune Checkpoints with Monoclonal Antibodies in Therapy of Cancer
The immune checkpoints are regulatory molecules that maintain immune homeostasis in physiological conditions. By sending T cells a series of co-stimulatory or co-inhibitory signals via receptors, immune checkpoints can both protect healthy tissues from adaptive immune response and activate lymphocyt...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6895894/ https://ncbi.nlm.nih.gov/pubmed/31717326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111756 |
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