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In Vitro Reconstitution of Yeast Translation System Capable of Synthesizing Long Polypeptide and Recapitulating Programmed Ribosome Stalling

The rates of translation elongation or termination in eukaryotes are modulated through cooperative molecular interactions involving mRNA, the ribosome, aminoacyl- and nascent polypeptidyl-tRNAs, and translation factors. To investigate the molecular mechanisms underlying these processes, we developed...

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Dettagli Bibliografici
Pubblicato in:Methods Protoc
Autori principali: Nagai, Riku, Xu, Yichen, Liu, Chang, Shimabukuro, Ayaka, Takeuchi-Tomita, Nono
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293373/
https://ncbi.nlm.nih.gov/pubmed/34287320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/mps4030045
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