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Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progression

Heterogeneity within a tumour increases its ability to adapt to constantly changing constraints, but adversely affects a patient’s prognosis, therapy response and clinical outcome. Intratumoural heterogeneity results from a combination of extrinsic factors from the tumour microenvironment and intrin...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Lüönd, Fabiana, Tiede, Stefanie, Christofori, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292450/
https://ncbi.nlm.nih.gov/pubmed/33824479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01328-7
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