STX2 Promotes Trophoblast Growth, Migration, and Invasion Through Activation of the PI3K-AKT Pathway in Preeclampsia

OBJECTIVES: Abnormal trophoblast behaviors during pregnancy contribute to the development of preeclampsia (PE). Syntaxin2 (STX2) has been shown to be a crucial epithelial mediator in numerous diseases. However, the functions of STX2 and the mechanisms underlying its role in PE remain largely unknown...

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Gepubliceerd in:Front Cell Dev Biol
Hoofdauteurs: Li, Yan, Sun, Xian-li, Ma, Chun-ling, Li, Chao, Zhan, Ying, Li, Wen-ting, Li, Can, Wang, Yi-hao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Cell and Developmental Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292021/
https://ncbi.nlm.nih.gov/pubmed/34295885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.615973
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