BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the western world. In previous studies, various proportion of patients was found to carry CD11b(+) or CD11c(+) B cells whose presence was an unfavourable prognostic factor. The exact mechanism however, how these receptors contribute...

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Bibliographic Details
Published in:PLoS One
Main Authors: Nagy-Baló, Zsuzsa, Kiss, Richárd, Demeter, Judit, Bödör, Csaba, Bajtay, Zsuzsa, Erdei, Anna
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291664/
https://ncbi.nlm.nih.gov/pubmed/34283878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254853
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