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Detection for disease tipping points by landscape dynamic network biomarkers
A new model-free method has been developed and termed the landscape dynamic network biomarker (l-DNB) methodology. The method is based on bifurcation theory, which can identify tipping points prior to serious disease deterioration using only single-sample omics data. Here, we show that l-DNB provide...
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| Pubblicato in: | Natl Sci Rev |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8291500/ https://ncbi.nlm.nih.gov/pubmed/34691933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwy162 |
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