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DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma

BACKGROUND: Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, biomarkers predicting long-term therapy responses are lacking. METHODS: A novel approach of reference-free deconvolution of large-scale DNA methylation data en...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Filipski, Katharina, Scherer, Michael, Zeiner, Kim N., Bucher, Andreas, Kleemann, Johannes, Jurmeister, Philipp, Hartung, Tabea I., Meissner, Markus, Plate, Karl H., Fenton, Tim R., Walter, Jörn, Tierling, Sascha, Schilling, Bastian, Zeiner, Pia S., Harter, Patrick N.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291310/
https://ncbi.nlm.nih.gov/pubmed/34281986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002226
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