DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma

BACKGROUND: Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, biomarkers predicting long-term therapy responses are lacking. METHODS: A novel approach of reference-free deconvolution of large-scale DNA methylation data en...

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Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Filipski, Katharina, Scherer, Michael, Zeiner, Kim N., Bucher, Andreas, Kleemann, Johannes, Jurmeister, Philipp, Hartung, Tabea I., Meissner, Markus, Plate, Karl H., Fenton, Tim R., Walter, Jörn, Tierling, Sascha, Schilling, Bastian, Zeiner, Pia S., Harter, Patrick N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2021
Onderwerpen:
Immunotherapy Biomarkers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291310/
https://ncbi.nlm.nih.gov/pubmed/34281986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002226
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