Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer

PURPOSE: Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorouracil metabolism and has been associated with some...

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Pubblicato in:Cancer Res Treat
Autori principali: Dong, Si-Qi, Wang, Tong-Min, Zhang, Jiang-Bo, He, Yong-Qiao, Xue, Wen-Qiong, Wu, Zi-Yi, Yang, Da-Wei, Cao, Lian-Jing, Huang, Jing-Wen, Li, Xi-Zhao, Zhang, Pei-Fen, Zheng, Xiao-Hui, Jia, Wei-Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Cancer Association 2021
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291172/
https://ncbi.nlm.nih.gov/pubmed/33285053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2020.457
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