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Shifts in the Neurobiological Mechanisms Motivating Cocaine Use with the Development of an Addiction-Like Phenotype in Male Rats
RATIONALE: The development of addiction is accompanied by a shift in the mechanisms motivating cocaine use from nucleus accumbens (NAc) dopamine D(1) receptor (D(1)R) signaling to glutamate AMPA-kainate receptor (AMPA-R) signaling. OBJECTIVE: Here we determined whether similar shifts occur for NAc-D...
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| Publié dans: | Psychopharmacology (Berl) |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8290931/ https://ncbi.nlm.nih.gov/pubmed/33241478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05732-4 |
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