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Mechanisms Underlying the Efficacy of Exercise as an Intervention for Cocaine Relapse: A Focus on mGlu5 in the Dorsal Medial Prefrontal Cortex

RATIONALE: Exercise shows promise as a treatment option for addiction, but in order to prevent relapse, it may need to be introduced early in the course of treatment. OBJECTIVE: We propose that exercise, by upregulating dorsal medial prefrontal cortex (dmPFC)-nucleus accumbens (NAc) transmission, of...

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Publicado en:Psychopharmacology (Berl)
Autores principales: Abel, Jean M., Nesil, Tanseli, Bakhti-Suroosh, Anousheh, Grant, Patrick A., Lynch, Wendy J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626681/
https://ncbi.nlm.nih.gov/pubmed/31161451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-019-05208-0
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