Human immunoglobulin from transchromosomic bovines hyperimmunized with SARS-CoV-2 spike antigen efficiently neutralizes viral variants

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with amino-acid substitutions and deletions in spike protein (S) can reduce the effectiveness of monoclonal antibodies (mAbs) and may compromise immunity induced by vaccines. We report a polyclonal, fully human, anti-SARS-CoV-2 im...

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Vydáno v:Hum Vaccin Immunother
Hlavní autoři: Liu, Zhuoming, Wu, Hua, Egland, Kristi A., Gilliland, Theron C., Dunn, Matthew D., Luke, Thomas C., Sullivan, Eddie J., Klimstra, William B., Bausch, Christoph L., Whelan, Sean P. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2021
Témata:
Passive SF – Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290372/
https://ncbi.nlm.nih.gov/pubmed/34228597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2021.1940652
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