The Multiple Roles of the Cytosolic Adapter Proteins ADAP, SKAP1 and SKAP2 for TCR/CD3 -Mediated Signaling Events

T cells are the key players of the adaptive immune response. They coordinate the activation of other immune cells and kill malignant and virus-infected cells. For full activation T cells require at least two signals. Signal 1 is induced after recognition of MHC/peptide complexes presented on antigen...

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Vydáno v:Front Immunol
Hlavní autoři: Dadwal, Nirdosh, Mix, Charlie, Reinhold, Annegret, Witte, Amelie, Freund, Christian, Schraven, Burkhart, Kliche, Stefanie
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290198/
https://ncbi.nlm.nih.gov/pubmed/34295339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.703534
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