Myofibroblast transcriptome indicates SFRP2(hi) fibroblast progenitors in systemic sclerosis skin

Skin and lung fibrosis in systemic sclerosis (SSc) is driven by myofibroblasts, alpha-smooth muscle actin expressing cells. The number of myofibroblasts in SSc skin correlates with the modified Rodnan skin score, the most widely used clinical measure of skin disease severity. Murine fibrosis models...

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Udgivet i:Nat Commun
Main Authors: Tabib, Tracy, Huang, Mengqi, Morse, Nina, Papazoglou, Anna, Behera, Rithika, Jia, Minxue, Bulik, Melissa, Monier, Daisy E., Benos, Panayiotis V., Chen, Wei, Domsic, Robyn, Lafyatis, Robert
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289865/
https://ncbi.nlm.nih.gov/pubmed/34282151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24607-6
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