Single-cell transcriptome and TCR profiling reveal activated and expanded T cell populations in Parkinson’s disease

Given the chronic inflammatory nature of Parkinson’s disease (PD), T cell immunity may be important for disease onset. Here, we performed single-cell transcriptome and TCR sequencing, and conducted integrative analyses to decode composition, function and lineage relationship of T cells in the blood...

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Published in:Cell Discov
Main Authors: Wang, Pingping, Yao, Lifen, Luo, Meng, Zhou, Wenyang, Jin, Xiyun, Xu, Zhaochun, Yan, Shi, Li, Yiqun, Xu, Chang, Cheng, Rui, Huang, Yan, Lin, Xiaoyu, Ma, Kexin, Cao, Huimin, Liu, Hongxin, Xue, Guangfu, Han, Fang, Nie, Huan, Jiang, Qinghua
Format: Artigo
Language:Inglês
Published: Springer Singapore 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289849/
https://ncbi.nlm.nih.gov/pubmed/34282123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-021-00280-3
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